Unwind in the heart of Louisville at 21c Museum Hotel Louisville, where art and luxury meet. Treat yourself to a rejuvenating massage at the onsite spa, then enjoy breakfast or dinner at Proof on Main. With a 24-hour gym, dry cleaning services, and helpful staff by your side.
Reviews
Loved by guests
9.4 out of 10, Loved by guests
Top-rated by travelersTop-rated by travelers
Popular amenities
Spa
Pet friendly
Free WiFi
Connecting rooms available
Main amenities (12)
Daily housekeeping
Restaurant and bar/lounge
Full-service spa
Breakfast available
24-hour fitness center
Valet parking
Room service
Massage/treatment rooms
24-hour business center
Business center
Meeting rooms
Limo/town car service
Feel at home (6)
Free cribs/infant beds
Connecting/adjoining rooms available
Private bathroom
Premium TV channels
Daily housekeeping
Laundry facilities
$156 nightly
The total price is $184
$184 total
Jun 28 - Jun 29
Total with taxes and fees
Why we love this property
Work and play paradise
Located in the city center's business district, this hotel offers a 24-hour business center and meeting rooms. Guests can unwind at the full-service spa or bar.
Dining that delights
This hotel tantalizes taste buds with a restaurant, bar, and full breakfast offerings. Culinary adventures await morning through evening.
Kentucky Bourbon Trail Visitor Center - 5 min walk - 0.4 km
KFC Yum Center - 8 min walk - 0.7 km
Getting around
Louisville Intl. Airport (SDF) - 10 min drive
Louisville, KY (LOU-Bowman Field) - 11 min drive
Restaurants
Heine Brothers' Coffee - 3 min walk
Swizzle - 8 min walk
Jockey Silks Bourbon Bar - 7 min walk
Vincenzo's Italian Restaurant - 5 min walk
Mussel & Burger Bar - 1 min walk
About this property
21c Museum Hotel Louisville
21c Museum Hotel Louisville offers a fantastic location, putting you just a 5-minute walk from Louisville Slugger Museum and Kentucky Bourbon Trail Visitor Center. Guests can indulge in deep-tissue massages at the spa, and Proof on Main serves breakfast, lunch, and dinner. This luxurious hotel also features a bar/lounge, a 24-hour fitness center, and a fitness center. Fellow travelers love the helpful staff and restaurant.
At a glance
DONE
Hotel size
91 rooms
Arranged over 4 floors
DONE
Arriving/Leaving
Check-in start time: 4 PM; Check-in end time: midnight
Contactless check-in available
Minimum check-in age: 21
Check-out time is 11 AM
Contactless check-out available
DONE
Special check-in instructions
Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools
DONE
Required at check-in
Credit card required for incidental charges
Government-issued photo ID may be required
Minimum check-in age is 21
DONE
Pets
Pets allowed (up to 50 lbs per pet)*
Service animals welcome
Food and water bowls available
WIFI
Internet
Free WiFi and wired internet access in public areas
Free WiFi and wired internet access in rooms
LOCAL_PARKING
Parking
Onsite valet parking (USD 32 per night; includes in/out privileges)
Wheelchair-accessible parking on site
Electric vehicle charging point on site
DONE
Other information
Smoke-free property
Property amenities
Food and drink
Full breakfast (surcharge) 7:00 AM–10:00 AM on weekdays and 8:00 AM–1:00 PM on weekends
Restaurant
Bar/lounge
Coffee/tea in a common area
Room service (limited hours)
What to do
Yoga classes
Golfing nearby
Hiking/biking trails nearby
Working away
24-hour business center
Meeting rooms
Computer station
Conference space (5000 square feet)
Services
24-hour front desk
Concierge services
Tour/ticket assistance
Limo or town car service
Dry cleaning/laundry services
Luggage storage
Multilingual staff
Porter/bellhop
Facilities
1 building/tower
Built in 2006
ATM/banking
Safe-deposit box at front desk
24-hour fitness center
Full-service spa
Massage/treatment rooms
Vegan dining options
Double-glazed windows
Uses some LED lighting
Comprehensive food waste policy
No plastic soda bottles
No plastic coffee stirrers
No plastic drinking straws
No plastic water bottles
Reusable cups only
Reusable tableware only
Banquet hall
Accessibility
Wheelchair accessible
Braille/raised signage
Elevator
Wheelchair-accessible path of travel
Wheelchair-accessible parking
Assistive listening devices available
Wheelchair-accessible registration desk
Room amenities
Be entertained
50-inch LCD TV
Premium cable channels
Home comfort
Air conditioning (climate-controlled)
Minibar
Espresso maker
Bathrobes
Iron/ironing board
Sleep well
Hypo-allergenic bedding
Down comforter
Blackout drapes/curtains
Soundproofed rooms
Premium bedding
Free crib/infant bed
Rollaway/extra bed (surcharge)
What to enjoy
In-room massage
Freshen up
Private bathroom
Designer toiletries
Hair dryer
Towels
Toothbrush and toothpaste (on request)
Toilet paper
Stay connected
Desk
Free WiFi and wired internet
Free local calls
Food and drink
Champagne service
Free bottled water
More
Daily housekeeping
In-room safe (laptop compatible)
Connecting/adjoining rooms available
Eco-friendly toiletries
Eco-friendly cleaning products provided
Uses some LED lighting
Water-efficient showers only
Special features
Spa
21c Spa has 2 treatment rooms. Services include deep-tissue massages, hot stone massages, sports massages, and Swedish massages. The spa is equipped with a sauna and a steam room. The spa is open daily.
Dining
Proof on Main - This fine-dining restaurant serves breakfast, brunch, lunch, and dinner. Guests can enjoy drinks at the bar.
Awards and affiliations
Eco-Certified Property
This property participates in Green Key Global, a program that measures the property's impact on one or more of the following: environment, community, cultural-heritage, the local economy.
Fees & policies
Mandatory fees
You'll be asked to pay the following charges by the property at check-in or check-out. Fees may include applicable taxes:
Service fee: USD 5.00 per accommodation, per stay
Optional extras
Full breakfast is offered for an extra charge of approximately USD 5 to 25 per person
Children & extra beds
Rollaway beds are available for USD 30.0 per night
Pets
Service animals exempt from fees
Pets are allowed for an extra charge of USD 40.00 per accommodation, per stay
Parking
Valet parking costs USD 32 per night with in/out privileges
Pool, spa, & gym (if applicable)
Reservations are required for massage services and can be made by contacting the property before arrival at the number on the booking confirmation
Policies
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.
Guests can rest easy knowing there's a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit, and window guards on site.
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation.
This property accepts credit cards. Cash is not accepted.
Credit cards accepted: Visa, Mastercard, American Express, Discover
This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels).
Also known as
21c Hotel Louisville
21c Hotel Museum
21c Louisville Hotel
21c Museum
21c Museum Hotel
21c Museum Hotel Louisville
21c Museum Louisville
Louisville 21c Hotel
Louisville 21c Museum
Museum Hotel 21c
21c Museum Hotel Louisville MGallery
21c Museum Louisville MGallery
Hotel 21c Museum Hotel Louisville - MGallery Louisville
Louisville 21c Museum Hotel Louisville - MGallery Hotel
21c Museum Hotel Louisville - MGallery Louisville
Hotel 21c Museum Hotel Louisville - MGallery
21c Museum Hotel MGallery
21c Museum MGallery
21c Museum Hotel Louisville
21c Museum Louisville Mgallery
21c Museum Louisville
21c Museum Hotel Louisville Hotel
21c Museum Hotel Louisville MGallery
21c Museum Hotel Louisville Louisville
21c Museum Hotel Louisville Hotel Louisville
Frequently asked questions
Does 21c Museum Hotel Louisville offer free cancellation for a full refund?
Yes, 21c Museum Hotel Louisville does have fully refundable room rates available to book on our site. If you’ve booked a fully refundable room rate, this can be cancelled up to a few days before check-in depending on the property's cancellation policy. Just make sure to check this property's cancellation policy for the exact terms and conditions.
Are pets allowed at 21c Museum Hotel Louisville?
Yes, pets are welcome, with a maximum weight of 50 lbs per pet. There's a charge of USD 40.00 per accommodation, per stay. Service animals are exempt from fees. Food and water bowls are available.
Is parking offered on site at 21c Museum Hotel Louisville?
Yes. Valet parking costs USD 32 per night. Electric vehicle charging is available.
What are the check-in and check-out times at 21c Museum Hotel Louisville?
Check-in start time: 4 PM; Check-in end time: midnight. Check-out time is 11 AM. Contactless check-in and check-out are available.
Is there an onsite casino at 21c Museum Hotel Louisville?
No, this hotel doesn't have a casino, but Horseshoe Southern Indiana Casino (22-min drive) is nearby.
What is there to do at 21c Museum Hotel Louisville and nearby?
Have fun with nearby activities such as hiking and practice your swing at the nearby golf course. Additional recreation onsite includes yoga. Indulge in a treatment at the spa and enjoy other amenities such as a 24-hour fitness center and spa services.
Are there restaurants at or near 21c Museum Hotel Louisville?
Yes, there's an onsite restaurant, Proof on Main.
What's the area around 21c Museum Hotel Louisville like?
21c Museum Hotel Louisville is in Downtown Louisville, a short 10-minute drive from Louisville Intl. Airport (SDF) and 3 minutes' walk from Louisville Slugger Museum. Travelers say that the hotel is in a great location.
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Reviews
21c Museum Hotel Louisville Reviews
9.4
Exceptional
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
9.6
Cleanliness
9.0
Amenities
9.4
Staff & service
9.6
Property conditions & facilities
Guest review summary
What guests liked
Convenient valet parking and nearby self-parking options were available. (6 reviews)
Breakfast was a good value and a highlight of the stay. (6 reviews)
From real guest reviews summarized by AI.
Popular mentions
Room
Service staff
Art
Location
Restaurant
Museums
Bed
Bar
Food
Bathroom
Reviews
Verified
10/10 Exceptional
May 31, 2026
Great museum themed hotel with character. The rooms were spacious and comfortable. Also located right of bourbon row which makes it easy to get around town. The valet service and staff were courteous and helpful. They can also charge your electric vehicle, which is included with your stay, while the car is parked.
Donald
Donald, 1-night trip
Verified
10/10 Exceptional
Feb 27, 2026
Nice room and close to all the distilleries. Great restaurant on site as well!
Brent
Brent, 1-night trip
Verified
10/10 Exceptional
Apr 12, 2026
Very clean and quiet room
Carter
Carter, 1-night trip
Verified
10/10 Exceptional
Feb 13, 2026
Large spacious room and super comfortable bed
Fascinating art and super bar and restaurant too
Great service from all staff
Amanada
Amanada, 2-night trip
Verified
10/10 Exceptional
Mar 3, 2026
The rooms and staff were great and the penguins were alive.
MARC
MARC, 1-night trip
Verified
10/10 Exceptional
Feb 4, 2026
Great room, super kind staff
Rachel
Rachel, 2-night trip
Verified
10/10 Exceptional
Apr 21, 2026
What a fun hotel! The red penguins were great to run into, the artwork in our room was awesome (the view outside wasn't), bourbon each night just added to the ambiance. The art in the gallery was varied so everyone could find something they liked. The limo and statue of David outside were a nice touch.
Carol
Carol, 2-night trip
Verified
10/10 Exceptional
Feb 11, 2026
Interesting Ambiente, very knowledgeable and friendly staff, great bar and good food in the restaurant with special choices.
Michael
Michael, 2-night trip
Verified
10/10 Exceptional
Feb 25, 2026
clean rooms, outgoing and friendly staff. The vibe is warm and fun, love the penguins
Douglas
Douglas, 1-night trip
Verified
10/10 Exceptional
Jan 30, 2026
Clean room, art work is beautiful, friendly staff .
Jeannie
Jeannie, 1-night trip
Verified
8/10 Very good
Jan 25, 2026
Great location for Whiskey Row in Downtown Louisville. Hotel was clean, artsy and has a great restaurant on site.
Stacy
Stacy, 2-night trip
Verified
10/10 Exceptional
Jan 7, 2026
All the staff were great! The rooms were clean the coffee was great. I would stay here again.
Lorie
Lorie, 2-night trip
Verified
10/10 Exceptional
Dec 9, 2025
Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!
Tammy
Tammy, 1-night trip
Verified
10/10 Exceptional
Jan 20, 2026
Staff very helpful. Rooms are spacious and clean. Lobby exhibits unique and interesting. Hotel well situated in downtown to access popular tourist attractions. Enjoyed our stay.
Barbara
Barbara, 3-night trip
Verified
8/10 Very good
Feb 15, 2026
Room was clean. The staff is helpful, nice, welcoming. Loved the art. Room is large. Great area.
Tamara
Tamara, 1-night trip
Verified
10/10 Exceptional
Feb 2, 2026
Really interesting setting for a hotel with all of the artwork. The room was clean and comfortable. We would have appreciated softer towels.
Lee Anne
Lee Anne, 2-night trip
Verified
10/10 Exceptional
Nov 10, 2025
Beautiful environment Helpful friendly staff
david
david, 1-night trip
Verified
10/10 Exceptional
Sep 28, 2025
Room was very clean and staff were very friendly.
Jennifer
Jennifer, 1-night trip
Verified
10/10 Exceptional
Nov 18, 2025
Room clean , comfortable and quiet.
Clark and Margaret
Clark and Margaret, 1-night trip
Verified
10/10 Exceptional
Sep 28, 2025
Amazing location and great hotel. Staff was great. Restaurant was delicious. Great location on Main Street!!
Jennifer
Jennifer, 4-night trip
Verified
10/10 Exceptional
Oct 27, 2025
21c Museum Hotel is a fun and unique experience. Beautiful rooms and centrally located to shops, restaurants and distilleries in Louisville.
Robin
Robin, 2-night trip
Verified
10/10 Exceptional
Jun 21, 2025
Great location, comfy beds, great service
Ilya
Ilya, 2-night trip
Verified
10/10 Exceptional
Oct 18, 2025
Perfect location for walking Louisville
earl
earl, 4-night trip
Verified
10/10 Exceptional
Dec 19, 2025
The room was great! The bar was fantastic. The hotel accommodated all of my requests. My husband and I have stayed here a few times. I'm truly grateful for the kindness of the staff.
Kevin
Kevin, 1-night trip
Verified
10/10 Exceptional
Sep 23, 2025
Fun place to stay! Eclectic, unique and eccentric decor. Really enjoyed the location and convenient, walkable access.