Hotels in Santa Cruz

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Check prices for these dates

Tonight
May 10 - May 11
Tomorrow
May 11 - May 12
Next weekend
May 16 - May 18
In two weeks
May 23 - May 25

Where to stay in Santa Cruz?

Alfonsina Hotel Boutique by Inboccaluppo
Outdoor pool

Alfonsina Hotel Boutique by Inboccaluppo

3.5 star property
9.6 out of 10, Exceptional, (33)
$103 nightly
The price is $103
May 24 - May 25
Alfonsina Hotel Boutique by Inboccaluppo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Santa Cruz

Showing deals for:May 23 - May 25

Image gallery for Hotel BY Armonia SCZ

Outdoor pool, sun loungers

Hotel BY Armonia SCZ

3.0 star property
Santa Cruz
10/10Exceptional (3 reviews)
20% off
Price is $143
$71 nightly
$143 total
Hotel BY Armonia SCZ
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Our prices for hotels in Santa Cruz are cheapest in February

See average prices and weather for all months

Price trends for hotels in Santa Cruz

Pricing is based on two traveler single night rates
May
$95
Average price during May is $95
Jun
$76
Average price during June is $76
Jul
$77
Average price during July is $77
Aug
$101
Average price during August is $101
Sep
$88
Average price during September is $88
Oct
$85
Average price during October is $85
Nov
$99
Average price during November is $99
Dec
$70
Average price during December is $70
Jan
$63
Average price during January is $63
Feb
$62
Average price during February is $62
Mar
$73
Average price during March is $73
Apr
$72
Average price during April is $72
Currently viewing crowd sizes and weather for May.

May

trending_downLow crowds
High 78°F / low 64°F. Sunny most days.
78°
weather_sun
May, Low crowds, average high temperature 78 degrees Fahrenheit, average low temperature 64 degrees Fahrenheit. Sunny most days.
64°
76°
weather_sun
June, Moderate crowds, average high temperature 76 degrees Fahrenheit, average low temperature 62 degrees Fahrenheit. Sunny most days.
62°
77°
weather_sun
July, Moderate crowds, average high temperature 77 degrees Fahrenheit, average low temperature 62 degrees Fahrenheit. Sunny most days.
62°
83°
weather_sun
August, Low crowds, average high temperature 83 degrees Fahrenheit, average low temperature 65 degrees Fahrenheit. Sunny most days.
65°
88°
weather_sun
September, High crowds, average high temperature 88 degrees Fahrenheit, average low temperature 69 degrees Fahrenheit. Sunny most days.
69°
89°
weather_sun
October, High crowds, average high temperature 89 degrees Fahrenheit, average low temperature 71 degrees Fahrenheit. Sunny most days.
71°
89°
weather_sun
November, Low crowds, average high temperature 89 degrees Fahrenheit, average low temperature 71 degrees Fahrenheit. Sunny most days.
71°
87°
weather_sun
December, Low crowds, average high temperature 87 degrees Fahrenheit, average low temperature 71 degrees Fahrenheit. Sunny most days.
71°
87°
weather_sun
January, Moderate crowds, average high temperature 87 degrees Fahrenheit, average low temperature 71 degrees Fahrenheit. Sunny most days.
71°
85°
weather_cloudy
February, High crowds, average high temperature 85 degrees Fahrenheit, average low temperature 71 degrees Fahrenheit. Cloudy most days.
71°
85°
weather_sun
March, High crowds, average high temperature 85 degrees Fahrenheit, average low temperature 70 degrees Fahrenheit. Sunny most days.
70°
83°
weather_sun
April, Moderate crowds, average high temperature 83 degrees Fahrenheit, average low temperature 68 degrees Fahrenheit. Sunny most days.
68°
Monthly weather averages (˚F)
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Top landmarks in Santa Cruz

Plaza 24 de Septiembre which includes heritage architecture and heritage elements as well as a large group of people

Plaza 24 de Septiembre

If you're planning a bit of sightseeing during your trip, head to Plaza 24 de Septiembre— just one of the monuments in central Santa Cruz.

See properties in Plaza 24 de Septiembre
Plaza 24 de Septiembre

Learn more about Santa Cruz

Santa Cruz is applauded for its cultural attractions such as Cine Center and Franco Aleman Cultural Center.

See all hotels in Santa Cruz
San Lorenzo Cathedral showing a garden
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What hotels do travelers recommend in Santa Cruz?
Alfonsina Hotel Boutique by Inboccaluppo, Chairú Eco Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are all accommodations that are popular with guests.
Where can I find free parking at my hotel in Santa Cruz?
These hotels offer the perk of free parking: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Hotel LP Equipetrol and Swissôtel Santa Cruz De La Sierra. There are 9 options you may want to check out on our site.
Can I book refundable hotels in Santa Cruz?
If you want the flexibility to change your plans to Santa Cruz, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay with my pet in Santa Cruz?
Your furry friend can stay with you at these pet-friendly hotels: Hotel LP Equipetrol, Ibis Santa Cruz DE LA Sierra and Swissôtel Santa Cruz De La Sierra. There are 10 options to choose from on our site.
Which Santa Cruz hotels do our guests like for their great location?
Our guests rave about the location of these properties: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Camino Real Hotel and Radisson Hotel Santa Cruz.
Where should I consider staying in Santa Cruz if I'm looking for a reasonably priced accommodation?
An inexpensive option worth considering is Hotel LP Equipetrol. You can browse all 14 choices on our site.
Where can I stay in Santa Cruz if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 20 vacation homes. In addition, you can choose from 132 apartments.
Where can I stay if I'm traveling to Santa Cruz with my kids?
Parents traveling with children may want to consider Marriott Santa Cruz de la Sierra Hotel, Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. You can also see 12 options on our site.
Where should I stay in Santa Cruz for a getaway with my partner?
Buganvillas Hotel Suites & Spa is a good option for a romantic getaway with your special someone.
Where should I stay in Santa Cruz if I'm looking for a luxury hotel?
Experience luxury when you stay at Marriott Santa Cruz de la Sierra Hotel, Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Additionally, browse all 6 options on our site.
What will the weather in Santa Cruz be like during my trip?
Santa Cruz is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.
Why should I book my Santa Cruz accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

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