Hotels in La Serena

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Check prices for these dates

Tonight
May 2 - May 3
Tomorrow
May 3 - May 4
This weekend
May 2 - May 4
Next weekend
May 9 - May 11

Where to stay in La Serena?

Casamolle Villa & Golf
42-inch Smart TV with premium channels, TV

Casamolle Villa & Golf

3.5 star property
10.0 out of 10, Exceptional, (3)
The price is $990
$990 per night
May 18 - May 19
Casamolle Villa & Golf
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in La Serena

Showing deals for:May 16 - May 18

Image gallery for Rusti.Ko Experiencias

Deluxe Studio Suite, Multiple Beds | Individually decorated, laptop workspace, free WiFi

Rusti.Ko Experiencias

2.5 star property
Vicuña
10/10Exceptional (1 review)
10% off
Price is $73
per night
$145 total
Rusti.Ko Experiencias
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Our prices for hotels in La Serena are cheapest in October

See average prices and weather for all months

Price trends for hotels in La Serena

Pricing is based on two traveler single night rates
May
$91
Average price during May is $91
Jun
$96
Average price during June is $96
Jul
$95
Average price during July is $95
Aug
$95
Average price during August is $95
Sep
$97
Average price during September is $97
Oct
$74
Average price during October is $74
Nov
$76
Average price during November is $76
Dec
$86
Average price during December is $86
Jan
$96
Average price during January is $96
Feb
$98
Average price during February is $98
Mar
$82
Average price during March is $82
Apr
$87
Average price during April is $87
Currently viewing crowd sizes and weather for May.

May

trending_downLow crowds
High 66°F / low 56°F. Sunny most days.
66°
weather_sun
May, Low crowds, average high temperature 66 degrees Fahrenheit, average low temperature 56 degrees Fahrenheit. Sunny most days.
56°
64°
weather_sun
June, Low crowds, average high temperature 64 degrees Fahrenheit, average low temperature 53 degrees Fahrenheit. Sunny most days.
53°
62°
weather_sun
July, Low crowds, average high temperature 62 degrees Fahrenheit, average low temperature 51 degrees Fahrenheit. Sunny most days.
51°
64°
weather_sun
August, Low crowds, average high temperature 64 degrees Fahrenheit, average low temperature 52 degrees Fahrenheit. Sunny most days.
52°
65°
weather_sun
September, Moderate crowds, average high temperature 65 degrees Fahrenheit, average low temperature 53 degrees Fahrenheit. Sunny most days.
53°
67°
weather_sun
October, Moderate crowds, average high temperature 67 degrees Fahrenheit, average low temperature 55 degrees Fahrenheit. Sunny most days.
55°
69°
weather_sun
November, High crowds, average high temperature 69 degrees Fahrenheit, average low temperature 58 degrees Fahrenheit. Sunny most days.
58°
71°
weather_sun
December, High crowds, average high temperature 71 degrees Fahrenheit, average low temperature 60 degrees Fahrenheit. Sunny most days.
60°
73°
weather_sun
January, High crowds, average high temperature 73 degrees Fahrenheit, average low temperature 62 degrees Fahrenheit. Sunny most days.
62°
74°
weather_sun
February, High crowds, average high temperature 74 degrees Fahrenheit, average low temperature 63 degrees Fahrenheit. Sunny most days.
63°
72°
weather_sun
March, Moderate crowds, average high temperature 72 degrees Fahrenheit, average low temperature 62 degrees Fahrenheit. Sunny most days.
62°
69°
weather_sun
April, Moderate crowds, average high temperature 69 degrees Fahrenheit, average low temperature 59 degrees Fahrenheit. Sunny most days.
59°
Monthly weather averages (˚F)
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Top landmarks in La Serena

Cisnes recien nacidos

Jardin del Corazon

Jardin del Corazon is in the heart of La Serena, so why not stop by during your stay. Want to stretch your legs some more? Head to Kokoro No Niwa Japanese Garden and Parque Japones Kokoro No Niwa, both a short walk away.

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Jardin del Corazon

La Serena and related destinations

La Serena is applauded for its cultural attractions such as President Gabriel González Videla Regional History Museum and Casa Gabriel Gonzalez Videla Historical Museum.

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Iquique is applauded for its cultural attractions such as Palacio Astoreca Cultural Center and Casa Collahuasi Art Museum.

See all hotels in Iquique

Villarrica is well-known for its attractions such as Lake Villarrica and Villarrica National Park.

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La Poza showing a lake or waterhole, mountains and forests

Asuncion is applauded for its cultural attractions such as Museum of Fine Arts and Museum of South American Football.

See all hotels in Asuncion

João Pessoa is well-known for its attractions such as Manaíra Shopping Mall and Handicraft Market. The city has something for everyone including sights like Manaíra Beach and Tamandare Sculpture within a tropical setting.

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A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers like in La Serena?
Hotel Chagual, Hostal La Serena and Cabañas MarSerena are all properties that our guests really like.
Where can I find free parking at my hotel in La Serena?
Park your car for free at these properties: Hotel Chagual, Hostal Avenue and sireno hostal.
Can I book refundable hotels in La Serena?
If you want the flexibility to change your travel plans to La Serena, most accommodations offer refundable* bookable rates. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay with my pet in La Serena?
Your animal companion is welcome at these pet-friendly hotels: Domos Dream hotel cabañas, Hostal La Mestiza - Hostel, and Piedra Blanca.
Which La Serena hotels do our guests like for their central location?
Our guests love Hotel Diego de Almagro La Serena for its great location.
Where should I stay in La Serena if I want an affordable accommodation?
Hotel Chagual is an accommodation you might want to consider that’ll save you money. You may want to browse all 9 choices on our site.
Where can I stay in La Serena if I want a vacation home instead of a traditional hotel?
If you’re looking for a good alternative to a hotel, look over our selection of 14 vacation homes. In addition, there are 202 apartments and 20 condos.
Where can I stay if I'm visiting La Serena with my children?
Your kids are welcome at Serena Suite Park Hotel and Mar De Ensueno.
Where should I stay in La Serena for a vacation with my partner?
Serena Suite Park Hotel is a great option for a romantic getaway.
Where should I stay in La Serena if I want a luxurious hotel?
An option for a luxury stay is Enjoy Coquimbo.
What will the weather in La Serena be like during my trip?
February and January are typically the warmest months in La Serena when the average temp is 67°F. July and August are the coldest months when the average temperature is 58°F. May and June are the months with the most rain.
Why should I book my La Serena hotel through Hotels.com?
There are lots of reasons to book your La Serena trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

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