Hotels in Mesopotamia

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Where to stay in Mesopotamia?

To Spiti tis Sofias

$67 nightly
The price is $78
Aug 5 - Aug 6
Total includes taxes and fees
To Spiti tis Sofias

Guesthouse Vissinokipos

9.4 out of 10, Exceptional, (10)
Guesthouse Vissinokipos

Hotel Anastassiou

2.0 star property
8.0 out of 10, Very Good, (64)
$45 nightly
The price is $54
Aug 1 - Aug 2
Total includes taxes and fees
Hotel Anastassiou

Limneon Resort & Spa

4.0 star property
9.2 out of 10, Wonderful, (182)
$108 nightly
The price is $134
Jul 27 - Jul 28
Total includes taxes and fees
Limneon Resort & Spa

Chloe Hotel

3.0 star property
10.0 out of 10, Exceptional, (83)
$98 nightly
The price is $118
Aug 1 - Aug 2
Total includes taxes and fees
Chloe Hotel

Calma Hotel & Spa

4.0 star property
9.6 out of 10, Exceptional, (34)
Calma Hotel & Spa

Orologopoulos Mansion

5.0 star property
9.6 out of 10, Exceptional, (33)
Orologopoulos Mansion

Esperos Palace Luxury & Spa Hotel

4.0 star property
9.0 out of 10, Wonderful, (83)
$96 nightly
The price is $121
Aug 1 - Aug 2
Total includes taxes and fees
Esperos Palace Luxury & Spa Hotel

Kyknos De Luxe Hotel

10.0 out of 10, Exceptional, (42)
$87 nightly
The price is $105
Aug 23 - Aug 24
Total includes taxes and fees
Kyknos De Luxe Hotel

Guest House Ilektra

9.8 out of 10, Exceptional, (6)
$51 nightly
The price is $61
Jul 24 - Jul 25
Total includes taxes and fees
Guest House Ilektra

Anesis Hotel

2.0 star property
9.0 out of 10, Wonderful, (9)
$56 nightly
The price is $66
Jul 24 - Jul 25
Total includes taxes and fees
Anesis Hotel

Arhontiko Christodoulou

2.0 star property
Arhontiko Christodoulou
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Mesopotamia

Learn more about Mesopotamia

The region around Mesopotamia is home to attractions such as Kastoria Lake and Dragon's Lair.

Check out the Mesopotamia hotels guests love right now

Frequently asked questions

How much does a hotel room cost in Mesopotamia?
You can choose a great hotel in Mesopotamia from $54 with properties to suit all budgets and needs. If you're after an affordable hotel in Mesopotamia that meets all of your requirements, set your filters and then sort the results by "Price: low to high". If you're a member, don't forget to sign in to your account to unlock more savings.
How can I find deals and earn rewards at Mesopotamia hotels?
Members can save up to 20% on select hotels in Mesopotamia. Plus, Silver, Gold and Platinum members earn extra rewards on VIP Access bookings, making each stay even more rewarding.

Can I book Mesopotamia hotels with free cancellation?
To book a refundable Mesopotamia hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are the top Mesopotamia hotels with a pool?
For a little extra luxury, discover some of the best Mesopotamia hotels with a pool. You can select "Pool" in the "Amenities" filter of your search on Hotels.com to find even more places to stay in Mesopotamia with a pool.
What are some popular hotels in central Mesopotamia?
If you're looking for hotels in central Mesopotamia, check out Chloe Hotel and Kyknos De Luxe Hotel. Travelers love Chloe Hotel for its location, as well as the winery, restaurant and outdoor tennis court this hotel offers. Kyknos De Luxe Hotel is another popular central hotel with a terrace, free parking and a hair salon.
Are all taxes and fees included in the Mesopotamia hotel prices shown on Hotels.com?
Hotels.com provides upfront pricing so you can relax knowing you won't be met with surprise additional fees or taxes when you're ready to confirm your booking. From the time you start your search on Hotels.com, the price you see is what you pay. This makes it much easier to compare properties and secure our best deal for your next getaway.
What hotels do travelers like in Mesopotamia?
Can I book a refundable hotel in Mesopotamia?
If you want the flexibility to change your travel plans to Mesopotamia, most hotels offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay if I'm visiting Mesopotamia with my children?
Your kids are welcome at To Spiti tis Sofias.
What will the weather in Mesopotamia be like during my trip?
The warmest months in Mesopotamia are usually August and July with an average temp of 69°F. January and February are the chilliest months when the average temp is 37°F. The rainiest months are November and December.
Why should I book my Mesopotamia hotel with Hotels.com?
There are plenty of reasons to book your Mesopotamia travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Mesopotamia

Find out more about Mesopotamia

If you're looking to discover somewhere new, look no further than Mesopotamia. Whether you're planning to stay for a night or for the week, the area around Mesopotamia has accommodations to fit every need. Search for hotels in Mesopotamia with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Mesopotamia hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Mesopotamia hotel deals are here with our lowest price guarantee.