Hotels in North Santee

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Check prices for these dates

Tonight
Apr 29 - Apr 30
Tomorrow
Apr 30 - May 1
This weekend
May 2 - May 4
Next weekend
May 9 - May 11

Where to stay in North Santee?

The George Hotel
Exterior

The George Hotel

3.5 star property
9.6 out of 10, Exceptional, (212)
The price is $257
includes taxes & fees
$233 per night
May 29 - May 30
The George Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in North Santee

Rice Museum which includes interior views

Rice Museum

If museums are on your list of things to see in Georgetown, then you might want to head to Rice Museum. Why not take a stroll along the beaches and watch the sunset while you're here? If you want to see more of the museums in Georgetown, you can easily walk to Georgetown County Museum.

See properties in Rice Museum
Rice Museum

Learn more about North Santee

The region around North Santee is home to attractions such as Hopsewee Plantation and Cape San Roman Beach.

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A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers recommend in North Santee?
Guests like Pet-Friendly Santee River Retreat w/ Private Dock!.
Can I book refundable hotels in North Santee?
If you’re looking for the flexibility to change your plans to North Santee, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in North Santee be like during my vacation?
The warmest months in North Santee are usually July and August with an average temp of 79°F. January and February are the chilliest months when the average temp is 53°F. The rainiest months are August and July.
Why should I book my North Santee hotel through Hotels.com?
There are plenty of reasons to book your North Santee travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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