Photo by Tony Oteromarrero

Hotels in Desert Center

Free cancellation options if plans change
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Tonight
May 4 - May 5
Tomorrow
May 5 - May 6
Next weekend
May 9 - May 11
In two weeks
May 16 - May 18

Where to stay in Desert Center?

Learn more about Desert Center

You can explore the area's natural beauty at Joshua Tree National Park during your stay.

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Christmas Eve 2017 Desert
Photo by Tony Oteromarrero
Open Photo by Tony Oteromarrero
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers like in Desert Center?
Guests like EQC Hotel 728.
Can I book a refundable hotel in Desert Center?
If you’re looking for the flexibility to change your plans to Desert Center, most properties provide refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Desert Center be like during my vacation?
July and August are typically the warmest months in Desert Center when the average temp is 93°F. December and January are the coldest months when the average temperature is 59°F. December and August are the months with the most rain.
Why should I book my Desert Center hotel through Hotels.com?
There are lots of reasons to book your Desert Center trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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