Photo by Cesare Zuccaro

Hotels in Sant'Isidoro

Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices

Check prices for these dates

Where to stay in Sant'Isidoro?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Sant'Isidoro

Learn more about Sant'Isidoro

Sant'Isidoro is well-known for its attractions such as Spiaggia di Sant'Isidoro and Porto Selvaggio and Palude del Capitano Regional Nature Park.

500px provided description: Giochi di colore al tramonto [#sky ,#sea ,#sunset ,#water ,#beach ,#sun ,#clouds ,#coast ,#coastline ,#twilight ,#horizon ,#sand ,#seascape ,#dawn ,#outdoors ,#dusk ,#idyllic ,#dramatic sky ,#jetty ,#horizon over water]
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*

Frequently asked questions

What hotels do travelers like in Sant'Isidoro?
Where can I get free parking at my hotel in Sant'Isidoro?
Casa Vacanza Marijò offers the perk of free parking.
Can I book refundable accommodations in Sant'Isidoro?
If you need the flexibility to change your travel plans to Sant’Isidoro, most properties offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay with my pet in Sant'Isidoro?
Your furry friend can stay with you at this pet-friendly hotel: Villa Itaca.
Where can I stay in Sant'Isidoro if I want a vacation rental instead of a traditional hotel?
If you want to find a good alternative to a hotel, look over our selection of 32 vacation homes. You can also book one of 52 apartments or 8 villas.
Where can I stay if I'm visiting Sant'Isidoro for a family-friendly vacation?
Your kids are welcome at Blu Salento Village.
What will the weather in Sant'Isidoro be like during my vacation?
The warmest months in Sant’Isidoro are usually August and July with an average temp of 78°F. January and February are the chilliest months when the average temp is 54°F. The rainiest months are November and October.
Why should I book my Sant'Isidoro hotel through Hotels.com?
There are plenty of reasons to book your Sant’Isidoro travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

https://www.hotels.com/lp/b/deals